Author/Editor     Cantello, R; Civardi, C; Cavalli, A; Varrasi, C; Gianelli, M
Title     Transcranial magnetic stimulation and epilepsy: the state-of-the-art
Type     članek
Source     In: Stalberg EV, de Weerd AW, Zidar J, editors. ECCN 98. 9th European congress of clinical neurophysiology; 1998 Jun 4-7; Ljubljana. Bologna: Monduzzi Editore,
Publication year     1998
Volume     str. 95-9
Language     eng
Abstract     Single(s)-, double(d)-, and repetitive(r)-pulse TMS explore some physiological variables of strong interest to epilepsy. Most of the information given by TMS points at the primary motor cortex (MI), but can have a more general value, at least when the antiepileptic drug action is concerned. TMS provided pathophysiological data useful to investigation, differential diagnosis and classification of epilepsy subtypes. s- and d-TMS have potential clinical value in studying the patient response to anticonvulsants. High-frequency r-TMS may be of use in the determination of the hemispheric dominance forlanguage. Low frequency r-TMS can depress the MI excitability, which may have potential therapeutic effects. Unfortunately, TMS is not an appropriate tool to activate the epileptic focus in patients being prepared for epilepsy surgery. The use of TMS must be restricted within the safety guidelines provided by the international research community.
Descriptors     EPILEPSY
DOMINANCE, CEREBRAL
EVOKED POTENTIALS, MOTOR
NEUROPHYSIOLOGY