Author/Editor		Cruccu, G; Capozza, M; Bastianello, S; Mostarda, M; Romaniello, A; Accornero, N
Title		3D brainstem mapping of "anatonomical" and "functional" lesions
Type		članek
Source		In: Stalberg EV, de Weerd AW, Zidar J, editors. ECCN 98. 9th European congress of clinical neurophysiology; 1998 Jun 4-7; Ljubljana. Bologna: Monduzzi editore,
Publication year		1998
Volume		str. 289-93
Language		eng
Abstract		We developed a 3D computer model of the human brainstem, constituted by 5268 voxels, each corresponding to a microvalume of about 2x2x2 mm. We use this model in patients with brainstem focal lesions, for two applications, which are related but methodologically different. 1. Quantitative assessment of the anatomical-functional association between the site of the "anatomical lesion" (as defined by MR imaging) and symptomatology. 2. Anatomical reconstruction of the "functional lesion" on the basis of symptomatology. The functional assessment was supported by clinical examination and neurophysiological testing of brainstem function, including early and late blink reflex, early and late masseter inhibitory reflex, jaw jerk, brainstem auditory evoked potentials, and somatosensory evoked potentials.
Descriptors		BRAIN STEM BRAIN MAPPING IMAGE PROCESSING, COMPUTER-ASSISTED ARTIFICIAL INTELLIGENCE EVOKED POTENTIALS, AUDITORY, BRAIN STEM EVOKED POTENTIALS, SOMATOSENSORY BLINKING MASSETER MUSCLE REFLEX