Author/Editor		Scully, Crispian
Title		Oral pathology of HIV infection and treatment
Translated title		Patologija ustne votline in zdravljenje pacientov okuženih z virusom HIV
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 67, št. Suppl 2
Publication year		1998
Volume		str. II-73-7
Language		eng
Abstract		Oral lesions are common in patients infected with human immunodeficiency virus (HIV), are often the presenting feature, and may herald deteoration in the general health and a poor prognosis. A wide range of oral lesions can be seen, notably fungal and viral infections. An overall picture of oral disease in the whole spectrum of HIV infection and the acquired immune deficiency syndrome (AIDS) has emerged, with a restricted series of fairly common oral lesions such as candidiasis, viral infections including hairy leukoplakia, gingival and periodontal disease and Kaposi's sarcoma However, a panoply of less common lesions can also be seen. Any treatment regimes used in persons with HIV infection should avoid further immunosuppression, avoid cariogenic agents (such as sucrose-containing medications), avoid agents aggravating symptoms such as xerostomia and must take into account adverse drug reactions and possible drug interactions, as well as the immune defect and bleeding tendency. Management of the HIV-infected person is a team approach and there should adways be close collaboration with the responsible appropriate colleagues, particularly when the oral lesions are not in isolation. Many of the oral lesions seen in HIV infection regress or clear during treatment with anti-HIV agents. This paper reviews the more common oral lesions and their management.
Summary		Lezije v ustni votlini so pogosto prisotne pri pacientih, okuženih z virusom imunske pomanjkljivosti pri človeku (HIV) in lahko napovedujejo slabšanja sistemskega zdravja in neugodno prognozo. V ustih okuženih pacientov lahko vidimo mnogo različnih lezij, najpogosteje kosti, ki jih povzročajo glivice in virusi. Pri pacientih z AIDS-om se je pokazala pestra slika ustnih bolezni, med katerimi so najpogostejša kandidiaza, virusne infkeicje vključno z lasasto leukoplakijo, gingivitis in parodontalna bolezen ter Kaposijev sakrom. Seveda pa je včasih mogoče opaziti mnogo manj običajnih lezij. Katerakoli oblika zdravljenja pri okuženih s HIV ne sme povzročiti dodatnega zaviranja imunskega sistema, ne sme vsebovati kariogenih agensov (kot so zdravila, ki vsebujejo saharozo), ne sme pospeševati kserostomije in mora upoštevati stranske učinke zdravil in njihovo medsebojno delovanje. Zdravljenje pacientov okuženih s HIV mora biti skupinsko v tesnem sodelovanju z drugimi specialisti, posebno takrat, kadar pacient nima lezij samo v ustni votlini. Mnoge lezije v ustni votlini se pri teh pacientih zmanjšajo ali izginejo med sistemskim zdravljenjem. Članek pregledno opisuje bolj pogoste lezije v ustni votlini okuženih pacientov in njihovo zdravljenje.
Descriptors		HIV INFECTIONS CANDIDIASIS, ORAL LEUKOPLAKIA, HAIRY PERIODONTAL DISEASES SARCOMA, KAPOSI'S SALIVARY GLAND DISEASES VIRUS DISEASES