Author/Editor		Soomets, Ursel; Haellbrink, Mattias; Zorko, Matjaž; Langel, Uelo
Title		From galanin and mastoparan to galparan and transportan
Type		članek
Source		Current Topics in Peptide & Protein Research
Vol. and No.		Letnik 2
Publication year		1997
Volume		str. 83-113
Language		eng
Abstract		Galparan and transportan are two galanin/mastoparan chimeras that display drastically different properties from the parent peptides. In contrast to mastoparan, galparan e.g. inhibits heterotrimeric G-proteins and has a biphasic effect on the Na+/K+-ATPase. Transportan is a cell penetrating peptide, potentially capable of high efficiency transport of large hydrophilic compounds, such as peptides and oligonucleotides, over the plasma membrane. In this article we review the actions of galparan and transportan as well as the literature on their parent peptides, galanin and mastoparan.
Descriptors		GALANIN CHIMERIC PROTEINS WASP VENOMS BIOLOGICAL TRANSPORT, ACTIVE STRUCTURE-ACTIVITY RELATIONSHIP