Author/Editor		Bobrowska-Haegerstrand, Malgorzata; Haegerstrand, Henry; Iglič, Aleš
Title		Membrane skeleton and red blood cell vesiculation at low pH
Type		članek
Source		Biochim Biophys Acta
Vol. and No.		Letnik 1371
Publication year		1998
Volume		str. 123-8
Language		eng
Abstract		Shapes of red blood cells at low pH were studied theoretically. It is assumed that the equilibrium shape of the blood cell corresponds to the minimum of its membrane elastic energy which consists of the bending energy and relative stretching energy of the bilayer, the stretching energy of the skeleton and the interaction energy between the skeleton and the bilayer. It is shown that the aggregation of the skeleton at low pH can cause the red blood cell shape transformation from the stomatocytic shape to the cell shape comosed of a spherical parent cell having the bilayer completely underlaid with the skeleton and spherical daughter vesicles without the skeleton.
Descriptors		ERYTHROCYTE MEMBRANE ERYTHROCYTES CELL SIZE HYDROGEN-ION CONCENTRATION LIPID BILAYERS MODELS, BIOLOGICAL