| Author/Editor | Poredoš, Pavel; Likar, Borut | |
| Title | Determination of oxemia in claudicant's leg during exercise usingtcpo2 measurement | |
| Type | članek | |
| Source | J Cardiovasc Diagn Proced | |
| Vol. and No. | Letnik 13, št. 1 | |
| Publication year | 1996 | |
| Volume | str. 15-20 | |
| Language | eng | |
| Abstract | Using tcpo2 measurement we can determine tissue oxygenation, which reflects the balance between oxygen delivery and oxygen consumption. At rest oxygen delivery in claudicants as in healthy persons exceeds oxygen consumption. Therefore tcpo2 values do not differentiate between healthy controls and patients with intermittent claudication. Only in higher stages of peripheral arterial occlusive disease is tcpo2 significantly reduced. In the present study we use tcpo2 monitoring to determine circulatory disturbances in patients with claudication during exercise. The study encompassed 28 patients with arterial occlusive disease of the lower limbs, claudication distance from 50 to 200 m, and 10 healthy volunteers. The degree of circulatory disturbance was also established by determining the ankle brachial pressure index. Exercise was performed on a special pedal ergometer that enabled precise determinations of work load of individual legs during a single excursion and following a full period of exercise. The total work capacity was calculated by computerized integration. tcpo2 was measured at the dorsum of the foot at rest and during exercise using a TCM-3 oxygen monitor. Using these data the degree of tcpo2 drop, the time delay to its onset, and its duration were calculated and related to work load performed. A total deficiency of oxygen delivery was also determined. The degree of tcpo2 drop in claudicants during exercise was related to ankle pressure decrease (r = 0.72, p < 0.05). The most significant negative correlation was found between ankle pressure decrease and the lag time from the beginning of exercise to onset of tcpo2 decrease (r = 0.84, p < 0.01). In healthy volunteers there were no significant changes in tcpo2 detected. There was also an inverse relation between oxygen drop and work performed up to the onset of ischemic pain (r = 0.67, p < 0.05). (trunc. at 2000 chars) | |
| Descriptors | INTERMITTENT CLAUDICATION EXERCISE ARTERIAL OCCLUSIVE DISEASES BLOOD GAS MONITORING, TRANSCUTANEOUS ANKLE BLOOD PRESSURE ERGOMETRY |