Author/Editor | Simonič, Igor | |
Title | Synthesis of some new potential biologically active 1,4-dihydropyridines | |
Type | članek | |
Source | Acta Chim Slov | |
Vol. and No. | Letnik 44, št. 1 | |
Publication year | 1997 | |
Volume | str. 95-104 | |
Language | eng | |
Abstract | In order to prepare some new pharmacologically interesting 1,4-dihydropyridines dimethyl and ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate (1a and 1b) were reduced to amine analogs (2) and then converted to amides (3, 4 and 8) and enamines (5, 7 and 8). Expected regioselectivity of reactions was observed. | |
Descriptors | DIHYDROPYRIDINES DRUG INDUSTRY TECHNOLOGY, PHARMACEUTICAL |