Author/Editor		Moser, E; Gomišček, G; Schuster, J; Echsel, H
Title		Systematic investigation of degradation effects on spin-spin relaxation times in mouse-liver by low resolution NMR
Type		članek
Source		Physiol Chem Phys Med NMR
Vol. and No.		Letnik 21, št. 2
Publication year		1989
Volume		str. 133-44
Language		eng
Abstract		Despite numerous work on spin-lattice (T1) relaxation in vitro, not much attention has been paid on spin-spin (T2) relaxation until now. In this study we are presenting spin-spin relaxation time measurements of mouse liver tissue in order to estimate the time-after-excision effects. The post mortem behaviour of excised tissue was investigated up to four hours in intervals of about nine minutes. The time course of liver T2 was determined for different temperatures (4 degrees - 40c degrees C) for female mice. In order to describe the similar behaviour of T2 and pH changes in mouse liver after excision, we are suggesting an empirical model to correlate this data. In contrast to T1 results published recently, we found no significant differences in liver T2 time course after excision due to different physiological states like sex, starvation or circadian rhythm. T1/T2-behaviour after tissue excision is discussed in an attempt to separate various relaxation mechanisms.
Descriptors		LIVER POSTMORTEM CHANGES HYDROGEN-ION CONCENTRATION MICE MICE, INBRED STRAINS MODELS, THEORETICAL NUCLEAR MAGNETIC RESONANCE TEMPERATURE TIME FACTORS