Author/Editor		Mihelič, Miro
Title		Regionalna kemoterapija napredovalega raka sečnega mehurja
Translated title		Regional chemotherapy of advanced urinary bladder cancer
Type		članek
Source		In: Tršinar B, Sedmak B, editors. Rak sečnega mehurja. Slovenski urološki simpozij; 1997 nov 7-8; Ljubljana. Ljubljana: Klinični oddelek za urologijio, Urološka sekcija SZD,
Publication year		1997
Volume		str. 105-9
Language		slo
Abstract		The survival of patients with advanced, recurrent and metastatic urinary bladder tumor is very poor. Local growth can cause complications. Urinary bladder cancer is a solid tumor with hypoxic areas, which are not suitable for conventional systemic chemotherapy. Hypoxic environment can be useful for the treatment of cancer in special conditions. Conditions for successful treatment are long exposure to cytotoxic drug at high concentrations and low or obsent blood outflow to prevent undesirable systemic toxic side effects. This can be achieved by intraarterial regional chemotherapy in hypoxic tissue (Aigner's technique). According to the author' experience tumor reduction and clinical response are with the presented technique surprisingly good and it is justified for paliative treatment.
Descriptors		BLADDER NEOPLASMS INFUSIONS, INTRA-ARTERIAL ANTINEOPLASTIC AGENTS PERFUSION, REGIONAL