Author/Editor     Avanzo-Velkavrh, Marija; Assejev, Vladimira; Novak-Antolič, Živa
Title     Vnetja v obporodnem obdobju: 1. pogostnost prisotnosti chlamydiae trachomatis in streptokoka skupine B pri porodnicah in njihovih novorojenčkih
Translated title     Infections in perinatal period: 1. colonization of mothers and their newborns with chlamydia trachomatis and group B streptococcus
Type     članek
Source     Zdrav Vestn
Vol. and No.     Letnik 67, št. 9
Publication year     1998
Volume     str. 515-8
Language     slo
Abstract     Background. The aim of this study was to find the incidence of healthy parturients at term colonized with Chlamydia trachomatis (CT) and Group B Streptococcus (GBS), the actuall transmission from mother to baby during labour, and the incidence of CT and GBS infection in newborns. The newborn may become ill with chlamydial conjunctivitis or chlamydial pneumonia, whereas the GBS infection triggers neonatal sepsis resulting in high mortality rate. The literature provides evidence that in the mother, colonized with CT, there is a 50% probability that her newborn will suffer from chlamydial conjunctivitis. The data in literature show that from 50% to 40% asymptomatic women are colonized with GBS. In 40-50% of women, GBS is present in the lower genital tract throughout the duration of pregnancy, and in 20-30% occasionally only. The GBS transmission from mother to newborn during labour is estimated to be as high as 70%. Methods. At the Department of Obstetrics and Gynecology, the smear for the detection of CT was taken from the cervix of parturients (n = 533), and the smear for GBS detection from the lower third of the vagina (n = 211). In newborns the conjuctival specimen for CT detection was taken on day 4 after birth, and nasopharyngeal specimen for GBS detection within the first 24 hours after birth. Six weeks after delivery, all the mothers enrolled in the study were sent a questionnaire enquiring whether their newborn had suffered from conjunctivitis or pneumonia. The study period was September 1984-April 1985. Results. CT was detected in 6.4% of mothers and in 10% of newborns; GBS was detected in 1.4% of mothers and in 7.6% of newborns.(Abstract truncated at 2000 characters)
Summary     Izhodišča. Želeli smo ugotoviti, koliko zdravih porodnic ob pričakovanem dnevu poroda je koloniziranih s Chlamydio trachomatis (CT) in streptokokom skupine B - Streptococcus agalactiae - (SSB), kolikšen je prenos teh dveh bakterij med porodm na novorojenčka in koliko novorojenčkov zboli zaradi okužbe s CT in/ali SSB. Novorojenček lahko zboli zaradi klamidijskega konjunktivitisa ali klamidijske pljučnice, okužbe s SSB pa povzroči sepso novorojenčka z visoko umrljivostjo. Iz literature je razvidno, da pri materi, kolonizirani s CT, obstaja 50% verjetnost, da bo njen novorojenček imel klamidijski konjunktivitis. Po podatkih iz literature naj bi bilo s SSB koloniziranih 15% do 40% asimptomatičnih žensk. Pri 40% do 50% nosečnic je SSB prisoten v spodnjem genitalnem traktu ves čas, pri 20% do 30% pa občasno. Prenos na novorojenčka med porodm naj bi bil 70%. Metode. Brise za ugotavljanje CT smo porodnicam (n = 533) jemali iz materničnega vratu, brise na SSB (n = 211) pa iz spodnje tretjine nožnice. Novorojenčkom smo jemali brise na CT iz očesne veznice 4. dan po rojstvu in na SSB iz nazofarinksa v prvih 24 urah po rojstvu. Šest tednov po porodu smo vsem ženskam, ki so bile vključene v študijo, poslali uprašalnik, na katerega so nam odgovorile, ali je otrok po odpustu iz porodnišnice prebolel vnetje očesne veznice ali pljučnice. Raziskava je potekala od septembra 1984 do aprila 1985. Rezultati. CT smo dokazali pri 6,4% mater in pri 10% novorojenčkov. SSB smo dokazali pri 1,4% mater in pri 7,6% novorojenčkov. Večji odstotek koloniziranih novorojenčkov kot porodnic je lahko posledica težav pri jemanju brisov med porodom zaradi anatomskih in fizioloških sprememb porodnih poti.(Izvleček prekinjen pri 2000 znakih)
Descriptors     PERINATOLOGY
CHLAMYDIA INFECTIONS
STREPTOCOCCAL INFECTIONS
PREGNANCY
LABOR
CHLAMYDIA TRACHOMATIS
STREPTOCOCCUS AGALACTIAE
RISK FACTORS