Author/Editor		Žolnir-Dovč, Manca; Eržen, Damijan; Šorli, Jurij; Zalokar, Polona
Title		Proti zdravilom odporni bacili tuberkuloze v Sloveniji - redkost ali vsakdanjost?
Type		članek
Source		In: Bole-Hribovšek V, Ocepek M, Klun N, editors. Zbornik s programom 2. kongres slovenskih mikrobiologov z mednarodno udeležbo; 1998 sep 27-30; Portorož. Ljubljana: Slovensko mikrobiološko društvo,
Publication year		1998
Volume		str. 18-21
Language		slo
Abstract		Drug - resistant tuberculosis represents a great problem in some parts of the world. And what is the situation in Slovenia? In 2856 patients registered from 1990 - 1997 susceptibility tests were performed. One hundred twenty-four patients (4.3%) had drug resistant tuberculosis. Multidrug - resistance was present in 34 cases (1.2%). The average primary resistance to at least one antituberculotic was 2.6% in the same period. IN the second part of the article we represent the compariosn of two susceptibility methods: the standard method of proportion (PM) on solid medium and the commercial MGIT AST SIRE method (MGIT). The mean time to MGIT results were 7.8 days and 21 days to PM. The accordance of both susceptibility methods was 99.0% for isoniazid, 99.5% for rifampin and 97.7% for ethambutol and streptomycin. At present in Slovenia drug - resistant tuberculosis is still low. Susceptibility testing by MGIT method is much faster as the standard method of proportion. However, the MGIT method can not totally replace the standard method for now.
Descriptors		TUBERCULOSIS TUBERCULOSIS, MULTIDRUG-RESISTANT MICROBIAL SENSITIVITY TESTS ANTITUBERCULAR AGENTS MYCOBACTERIUM TUBERCULOSIS