Author/Editor		Geerlings, SE; Starčič, M; Brouwer, EC; Hoepelman, AIM; Gaastra, W
Title		Virulenčni dejavniki uropatogenih sevov bakterije Escherichia coli, izoliranih iz pacientk z diabetesom
Type		članek
Source		In: Bole-Hribovšek V, Ocepek M, Klun N, editors. Zbornik s programom 2. kongres slovenskih mikrobiologov z mednarodno udeležbo; 1998 sep 27-30; Portorož. Ljubljana: Slovensko mikrobiološko društvo,
Publication year		1998
Volume		str. 35-8
Language		slo
Abstract		Most urinary tract infections (UTI) are caused by Escherichia coli (E. coli). The risk for UTI is even higher in diabetic females. One of the possibilities for the higher risk of diabetic females for UTI might be the presence of more virulent E. coli strains in urinary tract. In our study we sceened 97 E. coli strains isolated from the urine of diabetic females for virulence factors: haemolysin, P-fimbrial adhesin (PAP), S-fimbrial adhesin (SFA), afimbrial adhesin (AFA), type 1 fimbriae, cytotoxic necrotizing factor (CNF), aerobactin and heme binding protein. 33 strains produced haemolysin. 77 strains were positive in the PCR with the primers specific for type 1 fimbriae. For other adhesins we found far less positive strains: 28 for SFA, 18 strains were positive for PAP, and only 5 for AFA. 16 strains were positive for CNF and 32 aerobactin. 4 strains were positive in the PCR with the primers specific for Heme binding protein. The strains tested produced far less virulence factors than strains isolated from non diabetic females suffering from cystitis or pyelonephritis.
Descriptors		ESCHERICHIA COLI ESCHERICHIA COLI INFECTIONS URINARY TRACT INFECTIONS DIABETES MELLITUS POLYMERASE CHAIN REACTION ADHESINS, ESCHERICHIA COLI VIRULENCE