Author/Editor     Bren, Andrej F; Kandus, Aljoša; Buturović, Jadranka; Koselj, Mira; Kaplan-Pavlovčič, Staša; Ponikvar, Rafael; Kovač, Damjan; Lindič, Jelka; Vizjak, Alenka; Ferluga, Dušan
Title     Hemolytic-uremic syndrome (HUS) after cyclosporine (CS) treatment in kidney graft recipients
Type     članek
Source     In: Bren AF, Ferluga D, Olsen S, et al, editors. Proceedings of the International conference on transplantation with emphasis on kidney; 1998 Oct 8-9; Ljubljana, Slovenia. Ljubljana: Medical faculty, Institute of pathology,
Publication year     1998
Volume     str. 67-9
Language     eng
Abstract     CS related HUS occurred early after transplantation in 7 patients (3.5%) with high CS blood trough levels. Clinical pourse was more severe in cadaveric graft recipients and related to more severe histomorphologic forms of thrombotic microangiopathy (TMA). However in most patients graft function improved only with the lowering of CS doseing, except in 1 patient, who was presensitized and in whom in spite of CS cessation and administration of antilymphocytic antibodies and prostacycline graft was lost.
Descriptors     KIDNEY TRANSPLANTATION
HEMOLYTIC-UREMIC SYNDROME
CYCLOSPORINE