Author/Editor | Koren, Srečko | |
Title | Interferoni - pomembni dejavniki v imunskem odzivu | |
Translated title | Interferons - important factors in immune response | |
Type | članek | |
Source | Med Razgl | |
Vol. and No. | Letnik 37, št. Suppl 5 | |
Publication year | 1998 | |
Volume | str. 33-7 | |
Language | slo | |
Abstract | Inferons are cytokines that play a central role in the regulation of the immune response. Although gamma interferon is the prime immunoregulator, alpha interferon and beta interferon also have various effects on the immune system. This review briefly summarizes the effects of interferons on B cells, T cells, polymorphonuclear neutrophils, monocytes (macrophages), NK cells, expression of cell membrane proteins and expression of adhesion molecules and chemokines. | |
Summary | Inferferoni so citokini, ki imajo osrednjo vlogo pri uravnavanju imunskega odziva. Čeprav je glavni imunoregulator interferon gama, na različne načine učinkujeta na imunski sistem tudi interferon alfa in interferon beta. Pregledni članek zgoščeno prikazuje, kako interferoni vplivajo na delovanje limfocitov B, limfocitov T, polimorfonuklearnih nevtrofilcev, monocitov (makrofagov) in celic NK in na izražanje celičnih površinskih beljakovin, adhezijskih molekul in kemokinov. | |
Descriptors | INTERFERONS IMMUNE SYSTEM B-LYMPHOCYTES T-LYMPHOCYTES |