Author/Editor		Matos, Tadeja
Title		Prognostični dejavniki preživetja pri bolnikih z invazivno obliko raka sečnega mehurja
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1998
Volume		str. 45
Language		slo
Abstract		Cancer of the urinary bladder represents 3.2% of all cancers, taking the eleventh place by frequency of occurrence. There were 165 new patients with invasive bladder cancer detected in 1994 in Slovenia. As elsewhere in the world, also in our country the incidence of this disease is on increase. Despite our endeavors, in the last decades, the survival of patients with muscle-invasive bladder cancer has not changed, being around 50% on average. In most countries radical cystectomy still remains the treatment of choice for those tumors. The clinical studies conducted worldwide during the past en years are concenred with patients treated for muslce-invasive bladder cancer by conservative approach. The results of those investiations are encouraging, since they indicate that the survival of patients receiving such treatment is comparable with the survival of patients trated by radical cystectomy. owing to this treatment approach, the bladdr can be preserved in approximately three fourths of the patients. Favorable prognosis is expected particularly in the patients in whom a complete response has been confirmed on intermediate treatment evaluation, after transurethral resection and chemotherapy. Inthese patients the conservative method represents an adequate treatment option. In order to enable correct selection of patients for this type of treatment already at the time of diagnosis, we studied the prognostic value of certain primary tumor and patient characteristics at the beginning of therapy. The study was carried out on a series of 105 patients included into the conservative treatment program from December 1988 to June 1995.(Abstract truncated at 2000 characters)
Descriptors		BLADDER NEOPLASMS NEOPLASM STAGING SURVIVAL ANALYSIS AGE FACTORS SEX FACTORS RISK FACTORS PLOIDIES HEMOGLOBINS