Author/Editor		Rus, Rina
Title		Vpliv različnih membran dializatorja na restitucijo ledvične funkcije in preživetje bolnikov pri zdravljenju akutne ledvične odpovedi
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1998
Volume		str. 33
Language		slo
Abstract		The aim of the prospective randomised clinical study was to assess the influence of permeability and/or adsorbability of the syntetic membrane of the dialyser on survival, restitution of renal failure and duration of hemodialysis treatment in the patients with acute renal failure requiring hemodialysis and multiorgan failure. Seventy-two pts from intensive care units of University Medical Center Ljubljana were randomised according to dialyser used during whole duration of hemodialysis treatment to the group A: dialyser F6 (low flux polisulfone, Fresenius, Bad Homburg, Germany) - 38 patients, aged 61+-15 yrs; and group B: dialyser Filtral 12 (high flux AN69S, Hospal, Industrie Meyzieu, France) - 34 patients, aged 62+-12 yrs. No significant differences were found between the groups as concerns etiology of acute renal failure, number of organs failed, incidence of oliguria before hemodialysis (group A - 39.5% pts oliguric before HD, group B - 41.2% pts oliguric before HD) and indication for starting hemodialysis treatment. Before starting hemodialysis APACHE II score was determined in all patients (Group A - 21.7; Group B - 22,6). Incidence of hypotension was higher in the group A (F6), as well as the net ultrafiltration rate per hour. Previously nonoliguric patients became oliguric during hemodialysis treatment in 61 % of patients in the group A and 70% in the group B, respectively, the difference being not statistically significant. We found out that 18.7% of patients survived in the group A and 20.6% of patients in the group B. Ten patients (26.3%) recovered renal function in the group A compared with 8 patients (23.5%) recovered in the group B. The median number of hemodialysis treatments needed before recovery of renal function was 11.2 days in group A and 10.7 days in the group B. (Abstract truncated at 2000 characters)
Descriptors		KIDNEY FAILURE, ACUTE HEMODIALYSIS MEMBRANES, ARTIFICIAL SURVIVAL RATE INTENSIVE CARE UNITS OLIGURIA APACHE HYPOTENSION MULTIPLE ORGAN FAILURE TREATMENT OUTCOME