Author/Editor		Brnić, Zoran; Drinković, Ivan; Hebrang, Andrija
Title		High-resolution ultrasound and power-Doppler - advances in pre-invasive diagnosis of solid breast lesions: our one-year experience
Translated title		Ultrazvok z visoko ločljivostjo in energijski Doppler - prednosti preinvazivnega diagnosticiranja solidnih lezij v dojki, izkušnje enoletnega dela
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 32, št. 4
Publication year		1998
Volume		str. 353-61
Language		eng
Abstract		The purpose of the study was to evaluate high-resolution ultrasound (HRUS) and power-Doppler (CDE) in the differentiation of malignant from benign solid breast lesions. Patients and methods: HRUS and CDE examinations of solid breast masses were carried out in 25 women. Gray-scale criteria of malignancy and benignity were considered. The vessels of the lesion were classified as penetrant, peripheral and non-detectable with CDE. Final diagnose was obtained cytologically and/or with biopsy. Results: HRUS detected more frequently irregularity of contours, heterogeneity and posterior attenuation than "classic" ultrasound. Lateral shadows in carcinomas were seen in a considerable number of cases, but this did not have any impact on the accuracy of diagnosis. HRUS facilitated the visualization of small carcinomas intraductal calcifications and papillomas. CDE detected flow in 15/25 lesions, of which 8 were malignant. Penetrant vessels were observed in 6/8 carcinomas and only in 2/17 benign changes; 6/11 fibroadenomas were avascular, and 4/11 with peripheral vessels. In 3/6 other benign lesions, the flow was shown with CDE. Conclusion: HRUS and CDE can successfully help in differentiation malignant from benign solid breast mass, and are a good adjunct to mammography and physical examination in the pre-invasive phas eof diagnostic process.
Summary		Raziskavo smo izvedli z namenom, da bi ocenili zmogljivosti ultrazvoka (UZ) z visoko ločljivostjo in energijskega Dopplerja pri razlikovanju med malignimi in benignimi solidnimi lezijami v dojki. Bolniki in metode. Z UZ z visoko ločljivostjo in energijskim Dopplerjem smo pregledali 25 žensk. Pri pregledu smo upoštevali Grayevo lestvico za določanje malignosti ali benignosti. Žilje v lezijah smo razvrstili v naslednje tri skupine: penetrantno žilje, periferno žilje in žilje, nedoločljivo z energijskim Dopplerjem. Diagnoza je bila dokončno potrjena s citološko preiskavo in/ali z biopsijo. Rezultati: Z UZ z visoko ločljivostjo smo bolj pogosto odkrili nepravilne oblike, nehomogenosti in razredčitve v ozadju, kot s klasičnim UZ. V razmeroma velikem številu primerov smo odkrili zasenčenje ob straneh, vendar takšna odkritja niso imela nobenega vpliva na natančnost diagnoze. Z UZ z visoko ločljivostjo se je izboljšala vidljivost manjših karcinomov, intraduktalnih kalcinacij in papilomov. Z energijskim Dopplerjem pa smo v 15/25 lezijah, od katerih jih je bilo kar 8 malignih, zasledili pretok. Penetrantno žilje smo opazili v 6/8 karcinomih in v samo 2/17 benignih spremembbah. Od 11 fibroadenomov je bilo 6 avaskularnih, 4 do 11 pa je imelo periferno žilje. V 3/6 drugih benignih lezijah smo z energijskim Dopplerjem odkrili pretok. Zaključek: UZ z visoko ločljivostjo in energijski Doppler lahko uspešno prispevata k boljšemu razlikovanju med benignimi in malignimi solidnimi lezijami v dojki in sta koristen dodatek k mamografski preiskavi in kliničnemu pregledu, preden se odločimo za bolj invazivne diagnostične postopke.
Descriptors		BREAST NEOPLASMS ULTRASONOGRAPHY, MAMMARY ULTRASONOGRAPHY, DOPPLER, COLOR