Author/Editor     Lee, Jeffrey R; Proulx, Gary M; Donaldson, Craig W; Orner, James B
Title     Systemic lupus erythematosus diagnosed with extreme skin reaction during radiation therapy: a case report
Translated title     Sistemski lupus eritematodes z izrazito kožno reakcijo med radioterapijo: prikaz primera
Type     članek
Source     Radiol Oncol
Vol. and No.     Letnik 32, št. 4
Publication year     1998
Volume     str. 401-6
Language     eng
Abstract     The use of breast conservation therapy in patients with collagen vascular disease is controversial. Initial reports demonstrated severe skin reactions in patients receiving radiotherapy who also had a diagnosis of systemic lupus erythematosus or sclerederma. However, a more recent case-control study found no increased incidence of complications in these patients compared to patients without collagen vascular disease. We report a case of a patient diagnosed with systemic lupus erythematosus after developing a severe skin reaction early during her course of breast radiotherapy. The clinical course of the patient is reviewed along with the controversies surrounding this clinical dilemna.
Summary     Še vedno si nasprotujejo mnenja o konzervirajočem zdravljenju bolnic s karcinomom dojke, ki imajo tudi kolagensko vaskulatorno bolezen. Poročali so že o resnih kožnih reakcijah pri bolnicah, ki so jih obsevali in so imele sistemski lupus eritematodes ali sklerodermo. Novejša študija primerov s kontrolami pa pri teh bolnicah ne kaže večjega števila komplikacij kot pri tistih brez kolagenske vaskulatorne bolezni. Prikazujemo primer bolnice, ki smo ji diagnosticirali sistemski lupus eritematodes kmalu po začetku obsevanja dojke, ker je razvila resno kožno reakcijo. Opisujemo klinični potek zdravljenja, ob njem pa tudi nasprotujoče dejavnike ter klinične dileme.
Descriptors     BREAST NEOPLASMS
LUPUS ERYTHEMATOSUS, SYSTEMIC
ADULT
RADIOTHERAPY