Author/Editor		Čižman, Milan
Title		Prizadetost osrednjega živčevja pri otroku, okuženim s HIV
Translated title		Effects of HIV infection on central nervous system in children
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 37, št. Suppl 4
Publication year		1998
Volume		str. 444-8
Language		slo
Abstract		World Health Organization estimate that by late 1996, 2,6 million children worldwide had been infected with HIV and 1,3 milllion had died as a result. Almost all HIV infected children acquire the virus from their mothers. HIV has the potential to affect all organ systems. Manifestations are diverse and include infectious and noninfectious complications. In general the course of HIV infection is more accelerated in children. Neuroencephlopathy occurs in 75-90 % in children over time. Children with AIDS suffer neurologic complication either from direct HIV infection of the central nervous system as in AIDS encephalopathy or corticospinal tract degeneration or by immune-dysfunction-related problems such as opportunistic, bacterial, viral infections, neoplasms, ocular complications, and cerebral vascular accidents.
Summary		Svetovna zdravstvena organizacija ocenjuje, da je bilo ob koncu leta 1996 na svetu 2,6 milijona otrok okuženih s HIV, 1,3 milijona jih je umrlo. Pri otrocih je vertikalni prenos (z matere na otroka) najpogostejši način okuibe s HIV. HIV lahko prizadene vse organe. Znaki so različni in vključujejo infekcijske in neinfekcijske zaplete. Nasplošno poteka okužba s HIV v primerjavi s potekom pri odraslih, pospešeno. Živčevje je pogosto (v 75-90 %) prizadeto v poteku okužbe s HIV. Zapleti na osrednjem živčevju so posledica direktnega učinka HIV, kot HIV encefalopatija ali degeneracija kortikospinalne proge, ali prizadetosti imunskega sistema, kar ima za posledico oportunistične, bakterijske, virusne okužbe, maligne bolezni in zaplete na ožilju in očeh.
Descriptors		HIV INFECTIONS AIDS DEMENTIA COMPLEX CHILD AIDS-RELATED OPPORTUNISTIC INFECTIONS LYMPHOMA, AIDS-RELATED PYRAMIDAL TRACTS