Author/Editor		Rener-Primec, Zvonka
Title		Imunsko pogojene bolezni živčevja
Translated title		Immune diseases of nervous system
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 37, št. Suppl 4
Publication year		1998
Volume		str. 449-59
Language		slo
Abstract		This chapter considers three groups of neurologic diseases, that result from a failure of normal immune response. One group consists of rheumaic diseases, particularly collagen vascular diseases. The second includes disorders of central and peripheral nervous system characterised by demielinization as a basic pathologic mechanism, as multiple sclerosis, acute disseminated encephalomyelitis, acute postinfectious poliradiculytis and others. The third group consists of conditions, where autoantibodies are present against some subtructural unites as in polimyositis, dermatomyositis, myastenia gravis and Sydenheim chorea. Symptoms and signs pathognomonic for each condition as diagnosis and treatment are briefly reviewed.
Summary		Sestavek obravnava obolenja, ki nastanejo kot posledica motnje v mehanizmih imunskega odgovora. Razvrstimo jih lahko v tri skupine. V prvi so sistemske revmatološke bolezni (kolagenoze), ki prizadenejo tudi živčevje; temeljni patološki proces se odvija na ožilju (vaskulitisi). V drugi so bolezni, kjer je demielinizacija vodilni patološki proces, za katerega menimo, da je tudi avtoimune geneze. Sem sodijo multipla skleroza, akutni diseminirani encefalomielitis, akutni postinfekcijski polinevritis in druge. V tretjo pa uvrščamo obolenja, kjer so avtoprotitelesa naravnana proti posameznim celičnim strukturnim podenotam: na primer polimiozitis, dermatomiositis, miastenija gravis in Sydenhaimova horea, če naštejemo le najbolj poznane. Opisani so patognomonični znaki in simptomi v klinični sliki posameznih obolenj, ključ do diagnoze in možnosti zdravljenja.
Descriptors		NERVOUS SYSTEM DISEASES AUTOIMMUNE DISEASES CHILD LUPUS ERYTHEMATOSUS, SYSTEMIC POLYARTERITIS NODOSA RHEUMATIC FEVER ENCEPHALOMYELITIS, ACUTE DISSEMINATED MYELITIS, TRANSVERSE POLYRADICULONEURITIS FACIAL PARALYSIS DERMATOMYOSITIS