Author/Editor		Peterlin, Borut; Petrovič, Danijel
Title		Gene therapy in cardiovascular disease
Type		članek
Source		In: Pajer Z, Štiblar-Martinčič D, editors. International symposium on cardiovascular diseases. Proceedings of the 29th memorial meeting devoted to prof. dr. Janez Plečnik; 1998 Dec 3-5; Ljubljana. Ljubljana: Medical faculty, Institute of histology and embryology,
Publication year		1998
Volume		str. 91-7
Language		eng
Abstract		Recent insights in the pathophysiology of cardiovascular disease (CDV) and developement of efficient gene technology procedures have made it possible to develop animal models for CDV gene therapy. Genes, identified in many hereditary disorders predisposing to CDV and pathological processes, such as atherosclerosis, thrombosis, restenosis, arterial hypertension, revascularisation, ischemia/reperfusion injury, heart failure and transplantant rejection, have become targets for new therapeutical strategies. The clinical application of gene therapy awaits the development of improved vectors and strategies to control the delivery of therapeutical genes and their expression in the host
Descriptors		CARDIOVASCULAR DISEASES GENE THERAPY DISEASE MODELS, ANIMAL HYPERLIPIDEMIA ARRHYTHMIA CARDIOMYOPATHY, CONGESTIVE CARDIOMYOPATHY, HYPERTROPHIC