Author/Editor		Polanec, Janja; Patzer, Jan; Grzybowski, Jacek; Štrukelj, Milan; Pavelič, Zlatko P
Title		Amount and avidity of IgG antibodies to Pseudomonas aeruginosa exotoxin A antigen in cystic fibrosis patients
Type		članek
Source		Pathol Oncol Res
Vol. and No.		Letnik 3, št. 1
Publication year		1997
Volume		str. 26-9
Language		eng
Abstract		Amount and adivity of serum IgG antibodies to pseudomonas aeruginosa exotoxin A in sera of 31 patients with cystic fibrosis (CF) was studied. Eight patients had P. aeruginosa isolated from the sputum on multiple occasions, while from 23 patients no P. aeruginosa was isolated. Amount of IgG antibodies to P. aeruginosa exotoxin A were significantly increased in the serum of patients with P. aeruginosa pulmonary coloniyation (<0.0001). On the contrary, serum IgG avidity in the colonized and in non-colonized CF patients was low (<10) and was statisticaly different when compared to the 30 age-matched healthy controls (p<0.0001). There was no change in IgG avidity in six chronically infected CF patients from whom we obtained serum samples after half a year period (p=0.55). (Pathology Oncology Research Vol 3, No 1, 26-29, 1997)
Descriptors		CYSTIC FIBROSIS PSEUDOMONAS AERUGINOSA IGG ENZYME-LINKED IMMUNOSORBENT ASSAY EXOTOXINS ANTITOXINS CHILD