Author/Editor		Gorišek, Borut; Kovač, Vilma
Title		Sindrom trombocitopenije izazvane heparinom
Translated title		Syndrome of heparin induced thrombocytopenia
Type		članek
Source		Liječ Vjesn
Vol. and No.		Letnik 120
Publication year		1998
Volume		str. 157-9
Language		cro
Abstract		Heparin represents the basis for drug treatment and preventoin of thrombosis. However heparin itself may produce side effects, among others two types of heparin-induced thrombocytopenia (HIT). The more frequnt type 1 occurs in about 10% of patients within the first days of treatment and disappears spontaneuosly without sequelae. HIT type 2 represents a far more serious complication occuring in 0.1-1% of patients somewhat later, between days 4 and 10 of heparin therapy, and may provoke severe arterial and venous thrombosis. Apart from differences in clinical picture, data regarding platelet count and platelet aggregation test are significant for diagnosis. Heparin should be discontinued immediately and another anticoagulant therpy introduced. We are presenting the case of patients with thrombosis of the left external iliac artery following surgery for ovarian cancer as a complication of HIT type 2, which was recanalized successfully and the leg was saved.
Descriptors		HEPARIN THROMBOCYTOPENIA HYSTERECTOMY THROMBOSIS