Author/Editor		Strojan, Primož; Aničin, Aleksandar
Title		Combined surgery and postoperative radiotherapy for cervical lymph node metastases from an unknown primary tumour
Type		članek
Source		Radiother Oncol
Vol. and No.		Letnik 49, št. 1
Publication year		1998
Volume		str. 33-40
Language		eng
Abstract		Purpose: During the 20-year period under study, 125 squamous cell carcinoma cases were detected among 234 patients with cervical lymph node metastases from an unknown primary tumor diagnosed in Slovenia. Fifty-eight patients were treated by surgery and post operative radiotherapy, 56 of whom were eligible for follow-up and treatment evaluation. Patients and methods: Ther were six females and 50 males ranging in age from 33 to 81 years (median 56 years). Neck dissection was performed in 48 patients, while eight patients underwent extirpation of a single lymph node metastasis. On histopathological examination, disease was assessed as pN1 in six patients, pN2 in 37 patients and pN3 in 13 patients. The degree of tumor differentiation was G1 in one patient, G2 in 26 patients, G3 in 22 patients and GX in seven patients. Extracapsular tumor spread was found in 37 out of 48 examined specimens. Postoperatively, the irradiation field covered different sites of possible occult primary in 48 patients and in eight patients it was limited to the involved side of neck. (Abstract truncated at 2000 characters).
Descriptors		NEOPLASMS, UNKNOWN PRIMARY LYMPHATIC METASTASIS NECK CARCINOMA, SQUAMOUS CELL NEOPLASM STAGING SURVIVAL ANALYSIS