Author/Editor		Lestan, Boris; Tomšič, Matija
Title		Reaktivni artritis
Translated title		Reactive arthritis
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 38, št. Suppl 1
Publication year		1999
Volume		str. 31-42
Language		slo
Abstract		Reactive arthritis belongs to the group of serologically negative spondyloarthropathies. it is a sterile joint infection that develops after a distant infection. It can be triggered by all microorganisms, but triggering infection most commnly originate in the urogenital organs and gastrointestinal tract and in the respiratory organs. Since it is systemic disease it often affects also extraarticular tissues, mainly eyes, skin and mucous membranes. Theories about the etiology and development are described. Diagnosis is based on the clinical grounds. Specific tests for the reactive arthritis are lacking. Diagnosis can be made after psoriatc arthritis, septic arthritis, rheumatoid and crystal induced arthritis, Bechet's disease, tuberculosis, sarcoidosis and HIV infection are excluded. Rest and cold pads are necessary to alleviate pain in the acute pahse. Non-steroid antirheumatic drugs are the mainstream in drug treatment. There is still debate about the corticosteoid use. Antibiotics are effective in the acute phase if the ineffective agent is recognized, while their use in chronic states is not conclusive. Immunosuppressive agents come into play in chronic and relapsing disease.
Summary		Reaktivni artititis sodi med serološko negativne spondioartropije. To je sterilno vnetje sklepa po predhodni nekslepni okužbi. Povzročajo ga načelno vsi mikroorganizmi, pogosteje pa nastane po okužbi sečil oz. spolovil, prebavil in dihal. Bolezen je sistemska in pogosto prizadene poleg sklepov tudi izvensklepna tkiva, najpogosteje oči, kožo in sluznice. Opisane so teorije o nastanku in razvoju bolezni in dokazi zanje. Diagnoza temelji na skrbni anamnezi in kliničnem pregledu. Za opredelitev reaktivnega artritisa ni specifičnih testov. Izključiti je treba predvsem psoriatični artritis, septični artritis, revmatoidni in s kristali povzročen artitis, Behcetovo bolezen, tuberkulozo, sakoidozo in okužbo z virusom HIV. V akutni fazi sta potrebni počitek in fiikalni pristop k lajšanju bolečine. Med zdravili zavzemajo osrednje mesto nesteroidna protivnetna zdravila. O uporabi kortikosteroidov ni enotnega mnenja v svetu. Antibiotiki so učinkoviti v akutni fazi, v kronični fazi pa je njihova uporaba nedorečena. Pri kroničnih ali ponavljajočih se oblikah je treba poseči tudi po imunosupresivnih sredstvih.
Descriptors		ARTHRITIS, RHEUMATOID