Author/Editor		Jereb, Matjaž
Title		Kožne spremembe pri sepsi
Translated title		Skin lesions in sepsis
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 38, št. Suppl 1
Publication year		1999
Volume		str. 77-83
Language		slo
Abstract		Skin lesions in sepsis could be the first and most important diagnostic sign. They are consequence of disseminated intravascular coagulation, direct vascular invasion and occlusion by bacteria or fungi, immune response, septic embolism and vascular effects of toxins. Sepsis mortality despite progress of intensive care medicine and beside many antibiotic remain high. Fast and appropriate therapy has critical influence on survival.
Summary		Kožne spremembe pri sepsi so lahko prvi in najpomembnejši diagnostični element. Nastanejo kot posledica diseminirane hintravaskularne koagulacije, neposredne žilne invazije oziroma zapore žile z bakterijami ali glivami, imunskih dogajanj, septičnih embolij in pa zaradi delovanja toksina na žile. Umrljivost zaradi sepse, kljub razvoju intenzivne medicine in ob številnih antibiotikih, ostaja visoka. Hitro in pravilno zdravljenje odločilno vpliva na preživetje.
Descriptors		SKIN MANIFESTATIONS SEPSIS DISSEMINATED INTRAVASCULAR COAGULATION EMBOLISM BACTERIAL TOXINS