Author/Editor		Cukjati, David; Reberšek, Stanislav; Karba, Renata; Miklavčič, Damijan
Title		Mathematical modeling of chronic wound healing
Type		članek
Source		Electro Magnetobiol
Vol. and No.		Letnik 17, št. 2
Publication year		1998
Volume		str. 237-42
Language		eng
Abstract		The wound-healing process has previously been modeled with exponential or with linear curves. In the present study, we proposed a new model called the delayed exponential model, and compared all three models. Assessment of the models was based on healing data for two large groups of pressure ulcers in spinal-cord-injured (SCI) patients. The first group consisted of conventionally treated wounds and the second group of wounds additionally treated with biphasic electric-current-pulse stimulation, which was aplied locally to the wound. Linear, exponential, and delayed exponential curves were fitted to experimental data (weekly measurements of the wound surface area). Numerical criteria, in the form of the least sum of squares of errors and goodness-of-fit, were calculated for each wound and model. Both numerical criteria showed that the delayed exponential model offers the best fit of the three models tested.
Descriptors		DECUBITUS ULCER ELECTRIC STIMULATION THERAPY MODELS, THEORETICAL