Author/Editor		Ahčan, Uroš
Title		Reinervacija kože po poškodbi perifernega živca pri človeku
Translated title		Reinervation of the human skin after peripheral nerve injury
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1998
Volume		str. 175
Language		slo
Abstract		During the last two decades the surgical treatment of peripheral nerve lesions has improved considerably, primarily due to the continuous development of microsurgical techniques and ultrafine nonreactive suture materials, as well as due to new knowledge and better understanding of neurobiology and neurochemistry of nerve regeneration which still beat the path in clinical practice. The literature contains no clear data about return of vegetative function of the human skin after complete lesion of a peripheral nerve. The velocity and time needed for restoration of this function and the influence of patient's age and other factors are still unknown. We do not know the importance of collateral reinnervaton from the uninjured neighbouring axons and expansive regeneration from the injured neighbouring nerves to the final skin function in human. The literature contains no accurate objective data on the end-stage sudomotor and sensory recovery in patients with upper extremity macroreplantation where conditions of nerve regeneration are specific and differences in nerve regeneration between replanted fingers and patients after microneurovascular toe-to-hand transfer with delayed microsurgical reconstruction. Retum of sensation is difficult to evaluate in children. Subjective clinical methods are often not reliable because of poor co-operation. Therefore we established a new method for objective measurement of sudomotor nerve regeneration: Sympathetic skin response (SSR) first described in 1984 has proved clinically useful in assesing disorders of the sympathetic fbers in clinical neurophysiology. Sympathetic Skin Response (SSR) was measured in 14 paediatric patients (age range 3-15 years, mean 7.2 years) following repair of lacerated upper limb peripheral nerves (median, ulnar or both). All nerves had been completely divided and were repaired by primary epineural repair. (trunc. at 2000 chars)
Descriptors		HAND INJURIES REPLANTATION SKIN MICROSURGERY SYMPATHETIC NERVOUS SYSTEM CHILD ADULT AUTONOMIC DENERVATION NERVE REGENERATION MEDIAN NERVE ULNAR NERVE AMPUTATION, TRAUMATIC NERVE TRANSFER SENSORY THRESHOLDS ACTION POTENTIALS NINHYDRIN SURGICAL FLAPS SWEATING ELECTROMYOGRAPHY