Author/Editor		Voga, Gorazd
Title		Sistemski transport in poraba kisika pri miokardnem infarktu
Type		monografija
Place		Ljubljana
Publisher		Medicinska fakulteta
Publication year		1998
Volume		str. 82
Language		slo
Abstract		Oxygen transport variables (DO2I, VO2I, OER, SV02) can be helpful for assessment of adequacy of cardiac output, for better determination and for therapeutic decisions. Patients and methods.Hemodynamic and oxygen transport variables were measured and calculated in 37 patients with confirmed AMI and clinical signs of left heart failure before and during first 24 hours of treatment. Patient were treated routinely (group A; PAOP < 18 mm Hg; CI > 2.5 l/min/m2), with nitroglycerin (group B; PAOP > 18 mm Hg; CI > 2.5 l/min/m2) or dobutamine (group C; PAOP > 18 mm Hg; CI < 2.5 l/min/m2). Results. Hemodynamic and oxygen transport variables did not differ from initial values in the group A. In the group B PAOP significantly decreased but other variables did not change significantly. In the group C CI, DO2I SvO2 significantly increased, PAOP decreased, VO2I was not changed. DO2I and VO2I did not differ in survivors and non survivors in the first 24 hours. However, only in survivors CI, DO2I and SVO2 increased during the treatment. Conclusions. DO2 is not helpful for diagnosis and monitoring of heart failure treatment, since it closely reflects changes in CO. Despite increased DO2, VOZ did not change significantly and increased OER remains the most important compensatory mechanism in patients with inadequate CO. SVO2 is a reliable measure of adequate CO and inotropic treatment is beneficial only in patients with low SV02. Hemodynamic and oxygen transport variables change rapidly during the treatment. Therefore, for relaible assessment and proper treatment of heart failure in patients with AMI, beside PAOP and CO, SV02 should be measured frequently or even continuously.
Descriptors		MYOCARDIAL INFARCTION HEART FAILURE, CONGESTIVE OXYGEN OXYGEN CONSUMPTION MIDDLE AGE AGED CATHETERIZATION, PERIPHERAL CATHETERIZATION, SWAN-GANZ BLOOD GAS ANALYSIS ELECTROCARDIOGRAPHY NITROGLYCERIN DOBUTAMINE HEMOGLOBINS CARDIAC OUTPUT STROKE VOLUME BLOOD PRESSURE LACTATES SURVIVORS