Author/Editor		Franjić, Branislav
Title		Diagnostična operacija za biopsijo dojke z lokalizacijo nepalpabilnih sprememb
Translated title		Breast biopsies for nonpalpable mammographic abnormalities
Type		članek
Source		Zdrav Vestn
Vol. and No.		Letnik 68, št. 2
Publication year		1999
Volume		str. 103-5
Language		slo
Abstract		Background. mammography is the only screening technique that allows breast concer to be detected at the preclinical stage. Mammographically identified suspicious lesions that are not apparent on clinical examination must be followed closely using appropriate methods including excisional biopsy. Morphological diagnosis is established by aspiration biopsy and localisation of the lesion followed by excisional biopsy. methods and patients. Sinse 1987, we have used a modified Frank needle with a wire for localising such lesions. The Affected area of the breast is excised in general anaesthesia. The biopsy specimen containing the wire is x-rayed and sent to the pathologist together with the radiograph. In the period 1987-1995, the described procedure was used in 24 patients aged 35-37 years with pathological changes detected incidentally on preventive examination. Results. Eight cases of occult carcinoma were established. Six patients (25%) had ductal carcinoma in situ (DCIS), and two had intraductal minimal carcinoma with lesions measuring up to 10 mm (8,3%). In one patient with DCIS a quadrantecctomy was performed in order to extend the excision into healthy tissue. For three patients with DCIS the described diagnostic procedure was also curative. The patients with clinically occult cancer were comparatively young, raning in age from 42 to 57 years, with a mean age of 47.8 years. Conclusions. Mammography, followed by localisation and excisional biopsy of suspicious lesions are valuable methods that contribute to prompt and reliable diagnosis of breast concer in asymptomatic patients between 40 and 50 years of age.
Summary		Izhodišča. Mamografija je edina presejalna tehnika, ki omogoča iskanje predkliničnih stadijev raka dojke. Mamografsko ugotavljeno sumljivo spremembo v dojki, ki je klinično nezaznavna, moramo spremljati vključno z odprto biopsijo. Morfološko diagnozo ugotovimo z aspiracijsko biopsijo (AB) ter z lokalizacijo in ekscizijsko biopsijo. Metode in bolniki. Od leta 1987 izvajamo lokalizacijo z modificirano Frankovo lokalizacijsko iglo z žico. Lokalizirani predel v dojki izrežemo v splošni anesteziji. Bioptični vzorec z žico vred rentgensko slikamo in vse skupaj pošljemo patologu. Rezultati. Opisani postopek smo izvedli med letoma 1987 in 1995 pri 24 bolnicah, starih od 35-37 let. Patološke spremembe so bile slučajno odkrite na preventivnem pregledu. Zaključki. ugotovili smo osem okultnih karcinomov. Šest bolnic (25 odstotkov) je imelo duktalni Ca in situ (DCIS), dve intraduktalni minimalni karcinom do 10 mm (8,3 odstotka). Pri eni bolnici z DCIS smo opravili kvadrantektomijo zaradi razŠiritve ekscizije v zdravo tkivo. Za tri bolnice z DCIS je bil opisani diagnostični postopek obenem kirurškoterapevtski. Ugotovili smo, da so bolnice s klinično nezaznavnim rakom mlajše, povprečna starost 47,8 let (42-57). Operacija za biopsijo dojke z lokaliacijo in mamografijo sta pomembni za boljšo in čimprejšo postavitev diagnoze v skupini asimptomatskih bolnic med 40. in 50. letom starosti.
Descriptors		BREAST NEOPLASMS BIOPSY MAMMOGRAPHY CARCINOMA, INFILTRATING DUCT