Author/Editor     Žargi, Miha; Smid, L; Fajdiga, I; Hočevar-Boltežar, I
Title     Laser induced fluorescence in diagnostic of laryngeal cancer
Type     članek
Source     Folia Otorhinolaryngol Pathol Respir
Vol. and No.     Letnik 4, št. 1-2
Publication year     1998
Volume     str. 66-9
Language     eng
Abstract     Differences between induced fluorescence of normal and malignant tissues offer new possibilities in early detection of laryngeal cancer. A Laryngeal Imaging Fluorescence Endoscopic system in which the fluorescence is induced by helium-cadmium laser blue light was evaluated. It obtains and displays a fluorescence pseudo-image of the observed site. The normal tissue appears green and the malignant tissue is red. Fluorescence intensity measurement is also possible. 60 patients were observed. In 42 laryngeal malignancy was suspected. Estimations of pathologic changes obtained during laryngomicroscopy and fluorescence imaging were compared to histopathological findings. The study shows that fluorescence laryngoscopy may be a useful complementary method for detecting laryngeal malignancies. Its efficacy is similar to efficacy of laryngomicroscopy, but the two methods improve diagnostics when used in combination.Key- words: laryngeal cancer, tumour borders,flourescence detection.
Descriptors     LARYNGEAL NEOPLASMS
LARYNGOSCOPY
FLUORESCENCE
LASERS