Author/Editor		Novak, Mojca; Prosen, Barbara
Title		Pogostnost bakterijske vaginoze in povezava s prezgodnjim porodom
Translated title		Incidence of bacterial vaginosis and its relation to preterm delivery
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 37, št. 4
Publication year		1998
Volume		str. 483-96
Language		slo
Abstract		Bacterial vaginosis is characterized by the presence of large amounts of anaerobic bacteria, Gardnerella vaginalis and Mycoplasma hominis in the vagina, where they replace the normally present lactobacilli. The condition is implicated as a possible cause of preterm delivery. In our study, bacterial vaginosis was diagnosed clinically and microbiologically. The incidence of bacterial vaginosis in 72 pregnant women attending the Clinic for Pathologic Pregnancy (5,5%) was lower than that in 100 women examined prior to artificalabortion at the Day Clinic (14%) and in 23 women evaluated at the Clinic for Sexually Transmitted Diseases (23,0%). The diference in incidence between the groups was not statistically significant. Factors found to be significantly associated with bacterial vaginosis included: smoking 15 or more cigarettes per day (odds ratio 7,15; 95% contidence interval 1,9-26,0) and age < 17 years at the first sexual intercourse (odds ratio 3,64;95% contidence interval 2,2-7,1). The incidence of bacterial vaginosis is higher among non-pregnant women than among pregnant ones (odds ratio 3,22;95% contidence interval 1,5-6,8), and in the first and second trimester of pregnancy than in the third (odds ratio 2,22; 95% contidence interval 0,9-5,2). Sexual habits and cigarette smoking seem to predisponse women to bacterial vaginosis. The condition may resolve spontaneously during pregnancy. The pH determination and amine odour of the vaginal discharge can be used as a reliable screening test, while Gram-stain reading of the vaginal smear is employed to corroborate the diagnosis. Because of the small size of the series studied, it was not possible to profe the relationship between bacterial vaginosis and preterm delivery.
Summary		Bakterijska vaginoza je stanje v nožnici, ko normalno prisotne laktobacile zamenjajo močno pomnožene anaerobne bakterije, Gardnerella vaginalis in Mycoplasma hominis. Je možen vzrok za prezgodnji porod. Bakterijsko vaginozo smo določili klinično in mikroskopsko pri ženskah na treh oddelkih Ginekološke klinike. Pogostnost bakterijske vaginoze je bila pri 72 nosečnicah v Ambulanti za patološko nosečnost nižja (5,5%) od pogostnosti pri 100 preiskovankah z Dnevne klinike pred umetno prekinitvijo nosečnosti (14,0%) in 13 preiskovankah v Ambulanti za spolno prenosljive bolezni (23,0%). Razlike niso statistično značilne. Večje tveganje za pojav bakterijske vaginoze imajo ženske, ki so imele prvi spolni odnos pred 17. letom (razmerje obetov 3,64; 95% interval zaupanja 2,2-7,1), in ženske, ki pokadijo 15 ali več cigaret na dan (razmerje obetov 7,15; 95% interval zaupanja 1,9-26,0). Bakterijska vaginoza je pri nenosečih ženskah pogostejša kot pri nosečih (razmerje obetov 3,22; 95% interval zaupanja 1,5-6,8) prav tako je vprvem in drugem trimesečju pogostejša kot v pozni nosečnosti (razmerje obetov 2,22; 95% interval nosečnosti 0,9-5,2). Povezava med bakterijsko vaginozo in spolnim vedenjem ter kajenjem verjetno obstaja, v nosečnosti lahko spontano mine. Kot presejalni test bi lahko služila določitev pH in aminskega vonja nožničnega izcedka, za dokončno potrditev je primernejše barvanje razmaza nožničnega izcedka po Gramu. Povezave med bakterijsko vaginozo in pojavov prezgodnjega poroda nismo mogli dokazati zaradi premajhnega števila preiskovank.
Descriptors		VAGINOSIS, BACTERIAL RISK FACTORS LABOR, PREMATURE HYDROGEN-ION CONCENTRATION VAGINAL SMEARS SLOVENIA GARDNERELLA VAGINALIS MYCOPLASMA HOMINIS