Author/Editor		Reberšek-Gorišek, Jelka
Title		Bolnišnične glivne okužbe
Type		članek
Source		In: Dragaš AZ, Lorenčič-Robnik S, Kotnik-Kevorkijan B, editors. Zbornik predavanj Bolnišnične okužbe; 1999 maj 21-22; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		1999
Volume		str. 239-47
Language		slo
Abstract		Hospital fungal infections may occur at different hospital departments. They are, however, most often present in the ICUs. During the past 10 years, morbidity and mortality due to fungal infections have been increasing. The most frequent causative agent is the Candida species, and within this group Candida albicans. The second most frequent causative agent is the Aspergillus species. There are numerous risk factors making the occurrence of infections possible. The most often mentioned are weakened immune response due to a basic disease, the administration of new and numerous antibiotics, the use of catheters. Most infections occur endogenously, a possible means of transfer is also by the hands of staff and by contaminated instruments. Colonization by fungi is frequently present and it is difficult to discern it from an infection. The clinical diagnosis of fungal infection is a difficult one to make. It is often based on persisting febrility, high levels of C-reactive protein and the ineffectiveness of broad range antibiotic therapy along with the presence of rich factors. Fungal infection is ascertained by isolating fungi in infected material, by tissue biopsy as well as by serologic investigations. Amphotericin B and fluconazol are the antimycotics most often applied in the treatment of fungal infections.
Descriptors		INTENSIVE CARE UNITS CROSS INFECTION MYCOSES CANDIDA RISK FACTORS CANDIDIASIS ASPERGILLOSIS