Author/Editor | Čemažar, Maja | |
Title | Predictive assays of tumor response to chemo and radiotherapy | |
Translated title | Napovedni testi za izid zdravljenja tumorjev po kemo in radioterapiji | |
Type | članek | |
Source | Radiol Oncol | |
Vol. and No. | Letnik 33, št. 2 | |
Publication year | 1999 | |
Volume | str. 127-36 | |
Language | slo | |
Abstract | Currently used predictive assays of treatment outcome of tumors treated by chemo- or radiotherapy and radiation damage of normal tissues are presented. This review is focused on the assays where tumor cells derived from the human tumors need to be cultured in in vitro conditions to perform the test. In addition, an overview of the clinical studies dealing with the correlation between predictive assays and treatment out-come or radiation damage to the normal tissues is given. | |
Summary | Predstavljeni so testi za napovedovanje izida zdravljenja tumorjev po kemo- in radioterapiji in poškodb normalnih tkiv po radioterapiji. Pregled je osredotočen na tiste teste, pri katerih je treba celice gojiti v pogojih in vitro. Poleg tega članek obravnava tudi korelacijo med napovednimi testi in izidom zdravljenja različnih vrst raka ter poškodbami normalnih tkiv. | |
Descriptors | SARCOMA, EXPERIMENTAL NEOPLASMS RADIATION INJURIES CELL SURVIVAL DNA DAMAGE MICE MICRONUCLEUS TESTS CHROMOSOMES CELL DEATH GENE EXPRESSION ANOXIA TREATMENT OUTCOME |