Author/Editor		Maraspin, Vera; Lotrič-Furlan, Stanka; Strle, Franc
Title		Ceftriaxone associated hemolysis
Type		članek
Source		Wien Klin Wochenschr
Vol. and No.		Letnik 111, št. 9
Publication year		1999
Volume		str. 368-70
Language		eng
Abstract		Summary. A 48-year-old immunocompetent women treated with ceftriaxone 2 g daily iv. for late Lyme borreliosis developed severe haemolytic anaemia. The patient had previously received the same antibiotic two times without any side effects. The first clinical signs began to appear on the seventh day of treatment. The patient developed severe anaemia with a haemoglobin level of 45 mg/I on day 10; thereafter she ceased to receive the antibiotic. The outcome was favourable. The clinical course and serologic results suggest that severe anaemia was induced by ceftriaxone and that drug adsorption as well as immune complex mechanisms were involved in the pathogenesis.
Descriptors		LYME DISEASE CEFTRIAXONE ANEMIA, HEMOLYTIC MIDDLE AGE