Author/Editor		Urlep-Šalinović, Vera
Title		Humani herpesvirusi in možnost prenosa s transfuzijo
Translated title		Human herpesviruses and the possibility of transmission by blood transfusion
Type		članek
Source		In: Reberšek-Gorišek J, Baklan Z, Kotnik-Kevorkijan B, editors. Okužbe s humanimi herpesvirusi. Zbornik predavanj in praktikum Bedjaničev simpozij z mednarodno udeležbo; 1999 jun 11-12; Maribor. Maribor: Splošna bolnišnica Maribor,
Publication year		1999
Volume		str. 119-26
Language		slo
Abstract		The possibility of transmitting human herpesviruses-particularly cytomegalovirus (CMV), Epstein-Barrvirus (EBV), human herpesvirus 6 (HHV 6) and human herpesvirus 8 (HHV 8) - by transfusion of blood components is presented. After transfusion of CMV infected blood, a severe form of disease, possibly with fatal outcome, may develop in preterm infants, noninfected immunocompromized and transplant patients. The prevalence of CMV in our population is high, among our voluntary blood it amounts to 75%. Blood testing for CMV antibodies is not considered an obligatory routine test for voluntary blood donors. For groups of patients at risk requiring transfusion, CMV negative blood is prepared as well as leucodepleted erythrocytes or thrombocytes containing < 10 6 leucocytes. With blood cell components containing leucocytes, EBV, HHV 6 and HHV 8 can also be transmitted. To prevent or decrease the possibility of herpesvirus transmission by transfusion, we only decide on transfusion after exhausting all other therapeutic possibilites. Patients at risk are given antivirus medication preventively.
Descriptors		BLOOD TRANSFUSION HERPESVIRIDAE INFECTIONS BLOOD DONORS CYTOMEGALOVIRUS HERPESVIRUS 4, HUMAN HERPESVIRUS 6, HUMAN HERPESVIRUS, KAPOSI'S SARCOMA-ASSOCIATED