Author/Editor     Tomaževič, T; Geršak, K; Meden-Vrtovec, H; Drobnič, S; Veble, A; Valentinčič, B; Kermavner, L; Virant-Klun, I; Žemva, J
Title     Clinical variables influencing the success of IVF/ET in the natural cycle
Type     članek
Source     In: Kakar S, Spinola P, editors. Advances in reproduction. 10th world congress on human reproduction: expanded abstracts of the ARTA mini symposium; 1999 May 4-8; Salvador, Bahia, Brazil. Kiawah Is, South Carolina: Reproductive health centre,
Publication year     1999
Volume     str. 303-9
Language     eng
Abstract     To study different clinical parameters in order to predict the success of IVF/ET in the natural cycle. Prospectively collected data on follicular growth monitoring, laboratory data and clinical results in 113 women with 196 unstimulated IVF/ET cycles for tubal infertility or endometriosis were retrospectively evaluated. Oocytes were retrieved in 170 (86%) of 196 cycles. There were 113 ETs: 59% of all natural cycles and 68% of 170 natural cycles with oocytes retrieved. The first 29 embryo-transfers were performed on the 2nd day and the following 88 embryo transfers were performed on the 4th day after oocyte retrieval. There were 34 clinical pregnancies. Twenty eight healthy babies were born at term - 14% per puncture, 16% per positive puncture, 24 % per transfer. Clinical variables and their possible influence on the results of IVF in natural cycle were evaluated.. There were no statistical differences between pregnancy rates per ET between higher (0.60-1.17 nmol) and Iower (0.40-0.59.nmo1/1) E2 concentrations on the day of hCG (30% vs. 30%), between early (10-14) and late (16-21 day) aspiration day ( 25% vs.32%), between smaller (16-18mm) and bigger (19-22mm) follicular diameters on the day of hCG (22% vs.31%), between 28 ETs on 2nd and 88 ETs on 4th day after oocyte retrieval (18% vs.32%), but there was significant difference (P<0.05) between cycles with thin (6-8mm) versus thick (9-12 mm) endometrium on the day of hCG (20% vs 36%).
Descriptors     EMBRYO TRANSFER
FERTILIZATION IN VITRO
INFERTILITY, FEMALE
ENDOMETRIOSIS
PREGNANCY
OOCYTES
ESTRADIOL