Author/Editor		Takač, Iztok
Title		Napovedni dejavniki pri raku jajčnikov
Translated title		Prognostic factors in ovarian cancer
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 38, št. 1
Publication year		1999
Volume		str. 91-6
Language		slo
Abstract		In ovarian cancer the recognition of the prognostic factors allows an accurate planning of treatment, monitoring of patients and evaluation of the course of disease. Some factors depend only on the characteristics of the cancer and the patient herself, others may be influenced by the method of treatment. Patients with well differentiated lower stage tumors, diploid DNA contents in tumor cells, negative lymph node findings, total operative cytoreduction, and improved general condition may hope for a favorable course of disease. Poorly differentiated tumors, aneuploid DNA contents in cells, remaining tumor after surgery, extensive metastases, increased tumor marker values after the operation, ascites, progressed stage, advanced age and poor general condition of the patient mean an unfavorable prognosis.
Summary		Upoštevanje napovednih dejavnikov pri raku jajčnikov omogoča pravilno načrtovanje zdravljenja, spremljanje bolnic in oceno poteka bolezni. Nekateri so odvisni le od lastnosti raka in bolnice same, na druge pa lahko vplivamo z načinom zdravljenja. Bolnice z dobro diferenciranimi tumorji nižjih stadijev, diploidno količino DNA v tumorskih celicah, negativnimi bezgavkami, popolno citoredukcijo pri operaciji in boljšim splošnim stanjem lahko upajo na ugoden potek bolezni. Slabše diferencirani tumorji, anevploidna količina DNA v celicah, preostali tumor po operaciji, obsežni zasevki, povišane vrednosti tumorskih označevalcev po operaciji, ascites, napredovali stadij, starost in slabo splošno stanje bolnic napovedujejo neugoden potek bolezni.
Descriptors		OVARIAN NEOPLASMS PROGNOSIS SURVIVAL ANALYSIS RISK FACTORS