Author/Editor		Černe, Darko; Bručan, Andrej
Title		Pomen srčnega troponina I v diagnostiki nekroze miokarda
Translated title		Cardiac troponin I in diagnostic work-up of myocardinal injury
Type		članek
Source		In: Bručan A, Gričar M, editors. Urgentna medicina: izbrana poglavja 5. Zbornik 6. mednarodni simpozij o urgentni medicini; 1999 jun 16-19; Portorož. Ljubljana: Slovensko združenje za urgentno medicino,
Publication year		1999
Volume		str. 223-28
Language		slo
Abstract		Measurement of only myoglobin and the percentage of CK-MB (activity) are sufficient in about 95% of all requests for laboratory diagnosis, confirmation or exclusion of myocardial injury. Most receantly cardiac troponin I (cTnl) was proposed to be more reliable marker for myocardial injury than CK, CK-MB or LDH. We evaluated several pathologic conditions where serum cTnl might be superior to the percentage of CK-MB. We confirmed that cTnl might be a useful marker for the late detection of myocardial injury, is more specific in case of injury of skeletal muscle enriched with CK-MB, is more specific in case of the presence of CK macro type II or I and is useful when myocardial and skeletal muscle injury are coincided. However unexplained elevated levels of cTnl were frequently detected in patients with chronic renal diseases.
Descriptors		MYOCARDIAL INFARCTION CREATINE KINASE ISOENZYMES TROPONIN I