| Author/Editor | Krachler, M; Rossipal, E; Mičetič-Turk, D | |
| Title | Trace element transfer from the mother to the newborn - investigations on triplets of colostrum, maternal and umbilical cord sera | |
| Type | članek | |
| Source | Eur J Clin Nutr | |
| Vol. and No. | Letnik 53 | |
| Publication year | 1999 | |
| Volume | str. 486-94 | |
| Language | eng | |
| Abstract | To investigate the trace element transfer from the mother to the newbom. Design: The concentrations of the eight essential elements calcium (Ca), cobalt (Co), copper (Cu), magnesium (Mg), manganese (Mn), molybdenum (Mo), tin (Sn), and zinc (Zn), and of the non-essential and toxic elements barium (Ba), beryllium (Be) bismuth (Bi) cadmium (Cd), cesium (Cs), lanthanum (La) lithium (Li), lead (Pb), rubidium (Rb), antimony (Sb), strontium (Sr), and thallium (T1) were determined in umbilical cord (n = 29) and corresponding matemal sera (n = 29) as well as in colostrum (n = 27). Results: Umbilical cord serum concentrations of Ca, Mn, and Zn were 120%,150%, and 148% of the maternal value, respectively. Maternal sera had twice the Cu concentrations found in healthy adults and five-times higher Cu than umbilical cord sera. Concentration ratios colostrum/maternal serum and colestrum/umbilical cord serum were approximately one for Co,1.4 for Mg, two for Ca Mn, and Sn five for Cu (maternal serum), eight for Mo, and ten for Zn. Concentrations of the toxic elements, Cd and Pb decreased in the order colostrum (Pb 2.6 microg/L; Cd 0.6 microg/L) matemal sera (0.8 microg/L; 03 microg/L) umbilical cord sera (0.4 microg/L; 0.2 microg/L). Maternal serum Ba and Rb was 182% and 66% of the umbilical cord value. For Sr and Li, an almost perfect correlation between umbilical cord and matemal sera was found. For Ba, Co, Cu, Mn, Zn none, and for Ca, Cs, Mn, Mo, Rb only weak positive correlations between these two compartments could be established. Conclusions: The results of this study indicate that an active transport mechanism for the transport of Ca, Mn, Rb, and Zn from the mother to the newborn exists, whereas Cs, Li, and Sr follow concentration gradients. As regards Cu, the placenta showed to have a blocking effect on the transfer from the mother to the baby. | |
| Descriptors | COLOSTRUM FETAL BLOOD MATERNAL-FETAL EXCHANGE TRACE ELEMENTS ADULT INFANT, NEWBORN PREGNANCY BIOLOGICAL TRANSPORT, ACTIVE REFERENCE VALUES |