Author/Editor		Sakaguchi, Shoiji; Uchida, Barry T; Timmermans, Hans A; Pavčnik, Dušan; Sakai, Yukimasa; Keller, Frederick S; Roesch, Josef; Yin, Qiang; Kichikawa, Kimihiko; Uchida, Hideo
Title		Twin-tube endografts for aortic aneurysms: an experimental feasibility study
Type		članek
Source		J Vasc Interv Radiol
Vol. and No.		Letnik 10
Publication year		1999
Volume		str. 1092-8
Language		eng
Abstract		Purpose: To explore feasibility of twin-tube endografts (TTEGs) for treatment of abdominal aortic aneurysm (AAA). Material and methods: AAAs were in six dogs by overdilation of Palmaz stents. TTEGs made of seven 9.5-mm-diameter Gianturco Roesch Z (GRZ) stents and ocovered with PTFE were depployed simultaneously from both femoral arteries through 10-F sheaths to exclude the AAA. Follow-up aortography was performed immediately and at 2,4, and 8 weeks. Two dogs were killed at 4 weeks and four were killed at 8 weeks. Gross and histologic examinations were performed. Results: AAA creation and TTEG placement were successful in all six dogs. TTEGs completely excluded AAAs in five dogs. Minor temporary perigraft leak was seen in one dog immediately after stent placement. Four dogs had YYEGs patent to determination at 8 weeks. In two dogs with oversized TTEGs, one of the twin endografts occluded at 2 weeks. At autopsy, TTEGs were formed in semicircular shape and histology did not show any significant inflammatory reaction. Conclusion: TTEGs show promise for treatment of AAA, with the potential of reducing the introductory sheath size. Further expermental studies, particularly with TTEGs extended into iliac arteries, are warranted.
Descriptors		AORTIC ANEURYSM, ABDOMINAL BLOOD VESSEL PROSTHESIS BIOCOMPATIBLE MATERIALS DOGS MATERIALS TESTING DISEASE MODELS, ANIMAL FEASIBILITY STUDIES NYLONS PROSTHESIS DESIGN STAINLESS STEEL TREATMENT OUTCOME