Author/Editor     Lakin, Paul C; Pavčnik, Dušan; Bloch, Robert D; Uchida, Barry T; Corless, Christopher L; Timmermans, Hans A
Title     Percutaneous transjugular kidney biopsy in swine with use of a side-cutting needle with a blunt-tipped stylet
Type     članek
Source     J Vasc Interv Radiol
Vol. and No.     Letnik 10, št. 9
Publication year     1999
Volume     str. 1229-32
Language     eng
Abstract     Purpose: To evaluate a new 19-gauge blunt-tipped, side-cutting, single throw transjugular biopsy needle for transvenous kidney biopsies. Materials and methods: Transjugular transvenous kidney biopsies were performed with a modified 70-cm biopsy needle utilizing fluoroscopic guidance in nine swine. Three tissue specimens were obtained with four biopsy device passes in five animals and three biopsy device passes in four animals. Renal arteriography and venography were performed immediately before and after renal biopsy. Five animals were killed immediately after biopsy. Four animals were allowed to recovre and underwent arteriography and venography prior to being killed, which varied from 1 to 6 weeks. Gross and histologic examinations of the biopsied kidney were performed after authanasia. A pathologist reviewed all biopsy spcimens for quality based on the number of glomeruli present. Results: Results of immediate and delayed arteriography and venography were normal in all cases,. HIstologic evaluation of all biopsy specimens demonstrated a range of two to 13 glomeruli per sample (mean, 6.5), with successful acquisition of the cortex. In one animal killed immediately after biopsy, a small subcapsular hematoma was present. The 19-gauge, side-cut biopsy needle with a blunt tip stylet proved to be efficacious for obtaining renal cortical samples in right swine kidneys via a transjugular approach.
Descriptors     KIDNEY
BIOPSY, NEEDLE
KIDNEY GLOMERULUS
RENAL ARTERY
RENAL VEINS
NEEDLES
JUGULAR VEINS
SWINE