Author/Editor     Kogoj-Rode, M; Šmid, L; Budihna, M; Rode, M
Title     Koncentracija kalcija in fosfata v slini bolnikov, obsevanih z radioterapijo
Translated title     Calcium and phosphate concentrations in the saliva of patients undergoing radiotherapy
Type     članek
Source     Zobozdrav Vestn
Vol. and No.     Letnik 54, št. 1
Publication year     1999
Volume     str. 3-7
Language     slo
Abstract     The influence of pilocarpine, a parasympathomimetic agent, and biperiden, an anticholinergic, on the secretion and composition of saliva was studied in 69 patients undergoing radiotherapy for cancer of the head and neck, with the salivary glands included in the irradiation field. The patients were randomized into three groups: group A received pilocarpine, group B received biperiden during radiotherapy and pilocarpine for 6 weeks after the completion of radiotherapy, while group C received no medication during or after radiotherapy. Electrolyte levels in the patients' saliva were measured before the beginning of radiotherapy, after a dose of 30 Gy, on completion of radiotherapy and 3,6 and 12 months after the completion of radiotherapy. All three groups of patients had increased salivary content of calcium and decreased levels of phosphate during radiotherapy.
Descriptors     HEAD AND NECK NEOPLASMS
PILOCARPINE
BIPERIDEN
SALIVATION
SALIVA
CALCIUM
PHOSPHATES