Author/Editor		Kansky, Andrej A; Sotošek, Borut
Title		Ploščatocelični karcinom ustne votline in ustnic
Translated title		Squamous cell carcinoma of the oral cavity and the lip
Type		članek
Source		Radiol Oncol
Vol. and No.		Letnik 33, št. Suppl 1
Publication year		1999
Volume		str. S96-102
Language		slo
Abstract		Squamous cell carcinoma of the oral cavity and the lip present about 6% of all cancers diagnosed each year and about 30% of all head neck cancers. The relationship beetwen tobacco exposure, alcoholabuse and poor dental hygiene and disease developement has been clearly proportional demonstrated. A clear dose-response relationship has been identified with a greater risk being directly proportional to intensity and duraton of exposure. Other possible etiologic agents are being investigated. Prognostic evaluation is based on clinical staging of the tumor, on histologic characteristic of the primary tumor and the lymph nodes. Selection of the therapy depends on multiple factors; three major types of therapeutic modalities are avaible; surgery, radiation and a combination of both surgery and radiation. The lip is the most common site in the cancer of the head and neck. The majority of these lesions occur on the lower lip and males. A principal ethiologic factor is sun exposure and use of tobaco. The prognosis is better, compared to other forms of oral carcinoma. Surgery is the mainstay of therapy.
Summary		Rak ustne votline predstavlja približno 6% rakavih obolenj in okoli 30% vseh tumorjev glave in vratu. Pomembni etiološki dejavniki so uporaba tobaka, uživanje alkoholnih pijačin slaba ustna higijena. Tveganje za nastanek bolezni je odvisno od trajanja in intenzitete škodljivih dražljajev. Prognoza je odvisna od ocene kliničnega štadija in histoloških značilnosti tumorja in regionalnih bezgavk. Na izbiro zdravljenja vplivajo različni dejavniki, v poštev pa pride kirurško zdravljenje, radioterapija in kombinacija kirurškega zdravljenja in radioterapije. Rak ustnic je najpogostejši tumor v zgornjem aerodigestivnem traktu. Največkrat se pojavi na spodnji ustnici pri moškem. Glavni etiološki dejavnik je izpostavljenost sončni svetlobi in kajenje. Prognoza je na splošno boljša kot pri ostalih karcinomih ustne votline. Kirurgija je glavni način zdravljenja.
Descriptors		MOUTH NEOPLASMS LIP NEOPLASMS CARCINOMA NEOPLASM STAGING