Author/Editor     Dolenšek, Janez
Title     Dejavniki tveganja za nastanek nenadne nepričakovane smrti dojenčkov
Type     monografija
Place     Ljubljana
Publisher     Medicinska fakulteta
Publication year     1999
Volume     str. 62
Language     slo
Abstract     Objective: European Concerted Action on Sudden Infant Death was set up with the following objectives: 1. To determine the extent to which infants in Europe are put to sleep in prone position and the relative risks associated with doing so. 2. To examine possible risks associated with other current infant care practices. 3. To re-assess risks now associated with other previously known risk factors. Design: Case-control data were assembled from 20 centres in Europe over different periods lasting between September 1992 and March 1996. Data from on-going surveys in Scandinavia, England, Ireland and Germany were combined with surveys using standard ECAS protocol that were set up in Austria, Belgium, England, France, Holland, Hungary, Italy, Poland, Russia, Spain, Slovenia and the Ukraine. The diagnosis of SIDS was based on autopsy. Between 1 and 4 controls per case, matched for age and date of birth, were randomly selected to represent normal infants. Data on 22 core variables, related to objectives, were available from all surveys. 38 additional variables were abstracted, although they were missing from some protocols. Two composite variables were constructed. Subjects: 745 cases of SIDS and 2145 controls from 20 centres in Europe. Method of Analysis: Univariate and multivariate logistic regression. Result of univariate analysis: - OR s for 7 factors were > 10: last found face down; birth weight <2000g, gestational age <35 weeks; mother smoked 30+ cigarettes per day before, during or after pregnancy; and <0,5 rooms per person in household. -ORs for thirteen other factors ranged between 5 and 10. -All variables except vaccination in the last 7 days and the use of hat were univariately statistically significant. Results of Multivariate Analysis: - Principal risk factors were remarkably independent and relative risks showed little evidence of inter-centre heterogeneity.(Abstract truncated at 2000 characters.)
Descriptors     SUDDEN INFANT DEATH
RISK ASSESSMENT
RISK FACTORS
EUROPE
MULTIVARIATE ANALYSIS
DEATH, SUDDEN