Author/Editor		Hvala, A; Kobenter, T; Ferluga, D
Title		Fingerprint and other organised deposits in lupus nephritis
Type		članek
Source		In: Vizjak A, Rozman B, Ferluga D, editors. Autoimmune systemic diseases. Proceedings of the 30th memorial meeting for professor Janez Plečnik; 1999 Dec 2-3; Ljubljana. Ljubljana: Faculty of medicine, Institute of pathology,
Publication year		1999
Volume		str. 59-61
Language		eng
Abstract		In 227 tissue samples obtained by kidney biopsy in 185 systemic lupus erythematosus (SLE) pateints we studied electromicroscopically the frequency and characteristics of organised deposits and their relation to other fibrillary structures.. Fingerprint-like forms of deposits were demonstrated in 32 of 185 (17,3%) patients. In the control group of 626 kidney biopsies of patients with primary renal and systemic diseases other than SLE no dingerprint-like deposits were found. Fingerprint-like deposits were found associated with mesangial-transmembranous glomerular deposits (87%), more often along the peripheral capillary glomerular basal membrane than within the mesangial matrix. In 3 samples 20-100 nm tubules nad in 2 samples 10 and 18 nm Congo red negative fibrils were found in SLE patients with no cryoglobulinemia. We conclude that fingerprint deposits are characteristic, diagnostically relevant for SLE and represents morphologically a homogenous group of deposits, unrelated to cryoglobulinemia. In 5 patients we found tubules and filaments which, by their morphology and their structural characteristics resemble the tubules in primary immunotactoid glomerulopathy and fibrils in primary fibrillary glomerulonephritis.
Descriptors		LUPUS ERYTHEMATOSUS, SYSTEMIC LUPUS NEPHRITIS BIOPSY MICROSCOPY, ELECTRON IMMUNOHISTOCHEMISTRY SLOVENIA