Author/Editor | Brzin, J; Kos, K; Trstenjak, M; Machleidt, W; Turk, V | |
Title | Kininogens: inhibitors of cysteine proteinases in plasma and a similar inhibitor in chicken egg white | |
Type | članek | |
Source | Biomed Biochim Acta | |
Vol. and No. | Letnik 45, št. 11-12 | |
Publication year | 1986 | |
Volume | str. 1385-90 | |
Language | eng | |
Abstract | Isolation, based on their inhibitory properties, is a fast and simple alternative method for the preparation of kininogens from human plasma. Pure native low M kininogen can be obtained in a much higher yied then with classical methods, provided that a similarly efficient inhibition of protelysis is included. Chicken egg white also contains a high M inhibitor of cysteine proteinases. It closelyresembles low M kininogen in its molecular weight, acidic isoelectric point and 1 2 inhibitor to enzyme molar binding ratio. Its relation to chicken serum kininogen is not known. | |
Descriptors | EGG WHITE KININOGENS PROTEASE INHIBITORS CHICKENS ELECTROPHORESIS, POLYACRYLAMIDE GEL ISOELECTRIC FOCUSING MOLECULAR WEIGHT |