Author/Editor     Brzin, J; Kos, K; Trstenjak, M; Machleidt, W; Turk, V
Title     Kininogens: inhibitors of cysteine proteinases in plasma and a similar inhibitor in chicken egg white
Type     članek
Source     Biomed Biochim Acta
Vol. and No.     Letnik 45, št. 11-12
Publication year     1986
Volume     str. 1385-90
Language     eng
Abstract     Isolation, based on their inhibitory properties, is a fast and simple alternative method for the preparation of kininogens from human plasma. Pure native low M kininogen can be obtained in a much higher yied then with classical methods, provided that a similarly efficient inhibition of protelysis is included. Chicken egg white also contains a high M inhibitor of cysteine proteinases. It closelyresembles low M kininogen in its molecular weight, acidic isoelectric point and 1 2 inhibitor to enzyme molar binding ratio. Its relation to chicken serum kininogen is not known.
Descriptors     EGG WHITE
KININOGENS
PROTEASE INHIBITORS
CHICKENS
ELECTROPHORESIS, POLYACRYLAMIDE GEL
ISOELECTRIC FOCUSING
MOLECULAR WEIGHT