Author/Editor		Kaplan-Pavlovčič, Staša
Title		Serološka diagnostika ledvičnih bolezni
Translated title		Serologic tests in renal disease
Type		članek
Source		Med Razgl
Vol. and No.		Letnik 38, št. Suppl 7
Publication year		1999
Volume		str. 61-7
Language		slo
Abstract		Serologic tests, when appropriately used, are helpful for clinical evaluation of patients presenting with various renal syndromes, especially immunologically-mediated renal disease.Although renal biopsy is necessary for definitive diagnosis, serologic testings provide useful information of glomerular immunologic injury before histologic proof and provides monitoring of therapy. Tests are of greatest value if their capabilities and limitations are well undestood. This review will provide insight into some currently available serologic tests for use in recognising immunologically mediated disease with their applications and limitations. Clinical approach in using serologic testing in major renal syndromes will be presented.
Summary		Serološki testi so pri pravilni uporabi pomembno dopolnilo za ugotavljanje diagnoze in prognoze predvsem imunološko pogojenih ledvičnih bolezni, pri katerih pa je za točno diagnozo najpogosteje potrebna ledvična biopsija. S serološkimi testi lahko ugotovimo diagnozo bolezni že pred ledvično biopsijo in spremljamo učinke zdravljenja. Za učinkovito uporabo seroloških testov je treba dobro poznati znake in simptome ledvičnih bolezni, ki sestavljajo klinične sindrome, s katerimi se bolezni ledvic kažejo, ter hkrati poznati prednosti in omejitve posameznega testa za ugotavljanje določene bolezni. V članku bodo predstavljeni splošni principi interpretacije seroloških testov in klinična uporabnost testov pri najpogostejših renalnih sindromih.
Descriptors		GLOMERULONEPHRITIS SERODIAGNOSIS ANTIBODIES, VIRAL ANTIBODIES, BACTERIAL AUTOANTIBODIES CRYOGLOBULINS KIDNEY FAILURE, ACUTE NEPHROTIC SYNDROME