Author/Editor		Princi, Tanja; Peterec, Daniel
Title		Autonomic nervous function in rabbit myocardium after atropine administration: evaluation by spectral analysis of R-R interval variability
Type		članek
Source		In: MEDICON '98. Proceedings of the 8th Mediterranean conference on medical and biological engineering and computing; 1998 Jun 14-17; Lemesos. Lemesos: University of Cyprus,
Publication year		1998
Volume		str. 1-6
Language		eng
Abstract		The fluctuations that underlie the spontaneous variability of the heart rate (HR) were investigated in rabbits using power spectral analysis. The experiments were performed using 14 younger adult rabbits, anesthetized i.p. with urethane. The first group (A) was injected with antropine sulphate 2 mg/kg bw i.v., the second group (B) was injected with the muscarinic blocker 0.5 mg/kg bw i.v., whereas the third grou (C), used as coontrol, was given saline. The surface electrocardiogram (ECG) was recorded at rest and after atropine or saline treatment. The computer program calculated a series of consecutive intervals as a function of beat numbers. From the tachogram power spectral density (PSD) was computed. Every spectral component was identified by the center frequency and quantified by its power. The results suggested a dose-dependent atropine effect on time and frequency domain of HR variability.
Descriptors		MYOCARDIUM ATROPINE HEART RATE RABBITS ELECTROCARDIOGRAPHY SPECTRUM ANALYSIS