Author/Editor		Štiblar-Martinčič, Draga; Pajer, Zdenka; Coer, A
Title		Morphometry of the FRTL-5 cells after irradiation
Type		članek
Source		Acta Biol Hung
Vol. and No.		Letnik 51, št. 1
Publication year		2000
Volume		str. 91-7
Language		eng
Abstract		The morphological changes of in vitro irradiated FRTL-5 cells and their ability to grow in semi-solid medium were studied morphometrically. FRTL-5 cells were grown in medium with 4 different concentrations of TSH (0, 0.1, 1, 10 mU/ml). After irradiation with 0 Gy, 2 Gy and 4 Gy, the cells were seeded on glass cover-slips and in methocel. Fourteen days after irradiation, the morphometric analysis of FRTL-5 cells and their nuclei was performed. The results showed that irradiation and different doses of TSH have influence on FRTL-5 cell size, more on their nuclei than on the cell as a whole. Growing of FRTL-5 cells in the methocel indicates the possible transformation of these cells after long-culturing in the TSH medium and after irradiation.
Descriptors		THYROID GLAND CELL LINE CELL SIZE THYROTROPIN CULTURE MEDIA